Corpus Callosotomy in Pediatric Intractable Epilepsy: Microsurgical Technique Implication and Variation

نویسندگان

  • Eun Kyung Park
  • Dong-Seok Kim
چکیده

Medically intractable epilepsy is considered for surgical intervention first for resection of localized area of brain in which cases seizure control is expected generally. Nevertheless, those with non-localizing lesions in the imaging studies as well as multifocal spikes in electroencephalography (EEG) are not candidates for the resective surgery. For palliative intervention, corpus callosotomy may be considered for these patients. Early detection of proper candidates for surgical intervention in pediatric patients with medically intractable seizures may give a better chance of recovering their developmental potential by protecting the brain from further epileptic discharges.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Stereotactic laser ablation of the splenium for intractable epilepsy☆

Partial or complete corpus callosotomies have been applied, traditionally via open surgical or radiosurgical approaches, for the treatment of epilepsy in patients with multifocal tonic, atonic, or myoclonic seizures. Minimally invasive methods, such as MRI-guided laser interstitial thermal ablation (MTLA), are being employed to functionally remove or ablate seizure foci in the treatment of epil...

متن کامل

Callosal role in generation of epileptiform discharges: quantitative analysis of EEGs recorded in patients undergoing corpus callosotomy.

OBJECTIVE Corpus callosotomy tends to decrease seizure frequency and severity rather than transforming the seizure pattern from a generalized form into a lateralized or a partial one. The finding implies that bisection of the corpus callosum (CC) disrupts the epileptogenicity itself. In order to gain further insight into the possible role played by the CC in intractable generalized epilepsy, qu...

متن کامل

Microsurgical endoscopy-assisted anterior corpus callosotomy for drug-resistant epilepsy in an adult unresponsive to vagus nerve stimulation

Because most of the corpus callosotomy (CC) series available in literature were published before the advent of vagus nerve stimulation (VNS), the efficacy of CC in patients with inadequate response to VNS remains unclear, especially in adult patients. We present the case of a 21-year-old female with medically refractory drop attacks that began at the age of 8 years, which resulted in the patien...

متن کامل

جراحی صرع مقاوم به درمان طبی، بیمارستان لقمان، 82-1376

Background: Regarding the complications of chronic intractable epilepsy, the presence of respectable lesions in many these patients that can be diagnosed with noninvasive sensitive techniques such as MRI and SPECT and the unrecognized significance of epilepsy surgery in our country, we have decided to review the management of medically intractable epilepsy in patients, who underwent epilepsy su...

متن کامل

Corpus callosotomy: A palliative therapeutic technique may help identify resectable epileptogenic foci

Corpus callosotomy has a long history as a palliative treatment for intractable epilepsy. Identification of a single epileptogenic zone is critical to performing successful resective surgery. We describe three patients in which corpus callosotomy allowed recognition of unapparent seizure foci, leading to subsequent successful resection. We retrospectively reviewed our epilepsy surgery database ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012